GeneTherapy
Can a new approach control seizures without surgery?
Can a new approach control seizures without surgery? A new approach using low-intensity focused ultrasound has been demonstrated to quiet a seizure-relevant brain circuit in an animal model without surgery. The technique involves briefly opening the blood-brain barrier, delivering an engineered gene therapy to a specific region, and then flipping an on-demand “dimmer switch” with […]
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Star-shaped cells make a molecule that can ‘rewire’ the brains of mice with Down syndrome – understanding how could lead to new treatments
Star-shaped cells make a molecule that can ‘rewire’ the brains of mice with Down syndrome – understanding how could lead to new treatments Researchers have discovered that delivering a protein called pleiotrophin (Ptn) to star-shaped cells in the brain can “rewire” the brains of mice with Down syndrome, reversing changes to neural circuits and improving […]
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Focused sound energy holds promise for treating cancer, Alzheimer’s and other diseases
Focused sound energy holds promise for treating cancer, Alzheimer’s and other diseases Focused sound energy holds promise for treating various diseases, including cancer, Alzheimer’s, and other conditions, by directing powerful beams of energy to specific disease targets in the body. Researchers have made significant advances in focused ultrasound technology, overcoming technical hurdles such as skull […]
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Binge drinking brake found in mouse brains, offering future path to treating alcohol abuse – new research
Binge drinking brake found in mouse brains, offering future path to treating alcohol abuse – new research Researchers have identified a small cluster of neurons in the medial orbitofrontal cortex that play a key role in suppressing binge drinking behavior. The discovery was made using a genetically modified mouse model that allowed researchers to map […]
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