ImmuneSystem
Team pinpoints brain cells that drive anxiety in mice
Team pinpoints brain cells that drive anxiety in mice Researchers at the University of Utah have identified two groups of brain cells in mice that regulate anxiety: Hoxb8 microglia, which act as a brake pedal to prevent anxiety, and non-Hoxb8 microglia, which act as an accelerator that promotes anxiety. The study found that when only […]
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Can noninvasive nasal drops kill deadly brain tumors?
Can noninvasive nasal drops kill deadly brain tumors? Researchers have developed a noninvasive nasal delivery method that successfully eliminated deadly brain tumors in mice by boosting the brain’s immune response. The technology uses precisely engineered nanostructures called spherical nucleic acids to deliver potent tumor-fighting medicine to the brain through nasal drops, which is less invasive […]
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How does your immune system stay balanced? A Nobel Prize-winning answer
How does your immune system stay balanced? A Nobel Prize-winning answer The Nobel Prize-winning discovery of regulatory T cells (Tregs) by Shimon Sakaguchi, Mary Brunkow, and Fred Ramsdell revealed a new layer of protection against autoimmunity, where these cells act as “security guards” to suppress rogue immune responses. FOXP3 is the molecular key that controls […]
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There are differences in asthma between the sexes
There are differences in asthma between the sexes A new study has identified differences in asthma behavior between males and females, including variations in symptoms, gene expression, and response to treatment. The study analyzed data from over 6,000 samples and found that 61 genes were differentially expressed by sex in adults with asthma, with many […]
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Can inflammation actually protect aging brains against decline?
Can inflammation actually protect aging brains against decline? A new study published in Cell Reports suggests that inflammation may actually protect aging brains against decline, challenging long-held assumptions about the immune molecule STING. Mice genetically engineered to lack STING had worse memory and movement problems, mimicking senility and frailty seen in people with dementia and […]
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Immune cells are key to teen brain wiring
Immune cells are key to teen brain wiring Researchers have discovered that microglia, the brain’s immune cells, play a key role in wiring the adolescent brain during adolescence. The frontal cortex, responsible for executive functions such as empathy and decision-making, undergoes profound changes during adolescence, which can set the stage for neurodevelopmental disorders like schizophrenia […]
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Mitochondria can sense bacteria and trigger your immune system to trap them – revealing new ways to treat infections and autoimmunity
Mitochondria can sense bacteria and trigger your immune system to trap them – revealing new ways to treat infections and autoimmunity Mitochondria have been found to play a key role in sensing bacterial activity and helping neutrophils trap and kill bacteria, revealing new ways to treat infections and autoimmunity. The mitochondria can detect specific bacterial […]
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E. coli use an ancient war trick to kill viruses
E. coli use an ancient war trick to kill viruses E. coli bacteria have discovered an ancient war trick to kill viruses by hijacking viral enzymes to produce an immune signal molecule that triggers a defense against the virus. The newly discovered “Kongming” defense system allows the bacterium to commit suicide, taking the virus down […]
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‘Flagging’ shows promise against tough cancers
‘Flagging’ shows promise against tough cancers Researchers have developed a new treatment approach called “flagging” that uses synthetic antigens to teach the immune system to recognize and eliminate cancer cells, offering promise against tough-to-treat cancers like brain, breast, and colon tumors. The experimental therapy works by marking tumor cells with a synthetic antigen delivered via […]
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From furry friends to fish, turning up the heat helps animals fight germs − how Mother Nature’s cure offers humans a lesson on fever
From furry friends to fish, turning up the heat helps animals fight germs − how Mother Nature’s cure offers humans a lesson on fever Fever is not caused by pathogens like SARS-CoV-2 or the flu, but rather by the body’s immune system response to infection. The body raises its internal temperature to create a hostile […]
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