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Immunotherapy

Why does cancer immunotherapy work for some and not others?

Why does cancer immunotherapy work for some and not others? A new study published in Nature found that naturally occurring autoantibodies can significantly boost or hinder the effectiveness of cancer immunotherapy by up to 10-fold. The researchers mapped autoantibodies from 374 cancer patients treated with checkpoint immunotherapy and 131 untreated healthy individuals, using a novel […]

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โ€˜Factoryโ€™ implant shows promise for fighting several cancers

โ€˜Factoryโ€™ implant shows promise for fighting several cancers Researchers have developed an implantable “factory” that produces cytokines to trigger potent immune responses against various cancers, including metastatic melanoma and pancreatic tumors. The IL-12 cytokine factory successfully recruits specialized immune cells called precursor exhausted T cells (Tpex cells), leading to a large population of tumor-targeting T […]

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