Neurodegeneration
Parkinsonās protein clumps drain brain cells of energy
Parkinsonās protein clumps drain brain cells of energy Parkinson’s disease protein clumps can drain brain cells of energy by breaking down adenosine triphosphate (ATP), a molecule responsible for powering cellular activities. The protein clumps, composed of alpha-synuclein, reshape themselves to trap ATP in a small pocket, causing it to break apart and release energy, similar […]
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Can blocking a circadian clock protein fight Alzheimerās?
Can blocking a circadian clock protein fight Alzheimerās? A new study published in Nature Aging suggests that blocking a circadian clock protein called REV-ERBĪ± may help reduce neurodegeneration in Alzheimer’s disease. The researchers found that inhibiting REV-ERBĪ±, either genetically or with a novel drug, led to increased levels of NAD+, a molecule used for cell […]
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Can immune cell ācouriersā deliver Alzheimerās therapy?
Can immune cell ācouriersā deliver Alzheimerās therapy? Researchers at University of California, Irvine have created “living cellular couriers” called microglia that can deliver disease-fighting proteins to specific areas of the brain, potentially improving treatment for Alzheimer’s disease and other neurological disorders. The microglia cells were engineered using CRISPR gene editing to secrete an enzyme that […]
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